别名：2,2-二甲基-3-丁烯酸
英文名称：2,2-dimethylbut-3-enoic acid
分子式：C6H10O2
Cas No.：10276-09-2
分子量：114.15
结构式：
规格：95%
外观：淡黄色液体
用途：基础原料、有机中间体、医药中间体
合成工艺如下：
2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol; 5 palladium on barium sulphate; hydrogen; diethyl ether;
Reactants are commercially availlable.
WRIGGLESWORTH, Joe, US2015/329529, A1, (2015), (62 pag.) (0726) A solution of 2,2-dimethylbut-3-yn-1-ol (PharmaBlocks) (3 g, 30.6 mmol) in dry diethyl ether (40 mL) was added 2,2?-(ethane-1,2-diylbis(sulfanediyl))diethanol (5.57 g, 30.6 mmol), followed by 5 percent Pd on barium sulphate (Aldrich) (6.51 g, 3.06 mmol). The mixture was degassed thoroughly refilling with nitrogen and stirred under an atmosphere of hydrogen at room temperature for 4 hours. Th e resulting mixture was filtered under reduced pressure, washing the catalyst with diethyl ether. The filtrate was concentrated carefully under reduced pressure to remove most of the solvent. The resu lting suspension was filtered and the filtrate concentrated under reduced pressure to afford the title compound; (0727) 1H NMR (400 MHz, CDCl3) delta 5.71 (1H, dd), 5.05-4.97 (2H, mults), 3.27 (2H, s ), 1.41 (1H, br mult), 0.95 (6H, s).
