Product name：3-BroMopyridine-2-thiol
MF：C5H4BrNS
Cas No.：65938-86-5
MW：146.18
Structure：
Purity：97%
Appearance：yellow solid
Product use：Basic raw materials, organic intermediates, pharmaceutical intermediates
The synthesis process is as follows:
sodium sulfide; water; DMFA;
Reactants are commercially availlable.
CHEN, Chixu, WO2011/159839, A2, (2011) [00287] Step C: 3-bromopyridine-2-thiolA mixture of 3-bromo-2-chloropyridine (0.769g, 4mmol) and sod ium sulfide (0.336g, 6mmol) in DMF (3mL) was heated under microwave irradiation at 130°C for 0.5 hou r. Water (50mL) and ethyl acetate (20mL) were added and the layers separated. The aqueous layer was acidified to pH 6 resulting in the formation of a precipitate, which was isolated by filtration and dried under vacuum to yield the product as a yellow solid (0.42g, 55percent).
