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产品推荐:5-苯基-2-三唑胺

名称:5-苯基-2-三唑胺
英文名称:5-phenylthiazol-2-amine
分子式:C9H8N2S

分子量: 176.23822
Cas No.:39136-63-5
结构式:image.png

规格:96%

外观:类白色固体

用途:基础原料、有机中间体、医药中间体

合成工艺如下:

ethanol;

Reactants are commercially availlable.
DESAI, Neil, WO2010/144394, A1, (2010) Example 17Compound 16 (3.0 g, 15.05 mmol) was added to a suspension of thiourea (1.4 g, 18.10 mmol) in ethanol. The reaction mixture was refluxed for 8h. After cooling, solvent was concentrated and re sidue was subjected to purification with DCM/MeOH to give 17 as yellow solid (2.3 g, 80percent). 1H NMR (400 MHz, DMSO-d6) delta 9.37 (bs, 2H, NH2), 7.82 (s,1Eta, Ar-H), 7.58-7.34 (m, 6Eta, Ar-H); ESI -MS: calcd for (C9Eta8N2S) 176, found 177[M+H] .