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欢迎询价737000-77-0(3-氟哌啶盐酸盐)

别名:3-氟哌啶盐酸盐

英文名称:3-Fluoropiperidine hydrochloride

分子式:C5H10FNHCl

Cas No.:737000-77-0

 

结构式:image.png

规格:95%

用途:基础原料、有机中间体、医药中间体

合成工艺如下:

hydrochlorid acid; 1,4-dioxane; dichloromethane;

Reactants can be synthesized in 1 step.

BALINT, J贸zsef, WO2015/150449, A2, (2015) To a suspension of 773 mg (3.80 mmo[) tert-buty[ (35)-3-f[uoropiperidine-1- carboxy[ate (stepl) in 45 mL dich[oromethane was added 9.5 mL (38 mmo[) 4 Mhydroch[oric acid in dioxane. The mixture stirred overnight at room temperature and was then concentrated under reduced pressure to give crude (35)-3- f[uoropiperidine hydroch[oride (531 mg) which was used in the next step without purification.