名称：3-氨基-6-氰基吡啶
英文名称：3-Amino-6-cyanopyridine
分子式：C6H5N3
分子量: 119.12
Cas No.：55338-73-3
结构式：
规格：95%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
carbamic acid; palladium 10 on activated carbon; methanol;
Reactants are commercially availlable.
ZHENG, Xiufang, WO2015/22301, A1, (2015) To a solution of 5-nitropyridine-2-carbonitrile (7.0 g, 46.9 mmol) in methanol (150 mL) was added 10percent palladium on carbon (2.0 g) and carbamic acid (7.0 g, 115 mmol). After being heated under reflux for 16 hours, the resulting mixture was filtered and the filtrate was concentrated in vacuo. The residue was dissolved in water (150 mL) and the resulting mixture was extracted with ethyl acetate (150 mL x 3). The organic layer was dried over sodium sulfate and concentrated in vacuo to afford 5.1 g of 5-aminopyridine-2-carbonitrile (yield was 9 1.3percent).
