中文名称：2,2-二乙氧基硫代乙酰胺
英文名称：2,2-Diethoxyethanethioamide
分子式：C6H13NO2S
Cas No.：73956-15-7
分子量：163.24
结构式：
规格：95%
用途：基础原料、有机中间体、医药中间体
合成工艺如下：
ammonium sulfide; ethanol;
Reactants are commercially availlable.
WELFORD, Richard, WO2015/75025, A1, (2015) To a solution of 2,2-diethoxyethanethioamide (9g) in EtOH (90m1) were added molecularsieve 3A (22g) and ethylbromopyruvate (6.8m1). The reaction mixture was stirred underreflux for 6.5h. The mixture was evaporated in vacuo and the residue w as diluted with EA.The molecular sieve was filtrated off and washed with EA. The org. layer was washed withNaHCO3, dried over MgSO4, filtrated off and evaporated in vacuo. The crude compound(14.3g of a brown oil) was used without purificati on in the next step. LC-MS (B): tR = 0.82mm; [M+H]: 260.12.
