名称：3,4-二氨基-5-碘苯甲酸甲酯
英文名称：3,4-Diamino-5-iodo-benzoic acid methyl ester
分子式：C8H9IN2O2
分子量: 292.07373
Cas No.：1258940-57-6
结构式：
规格：95%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
SnCl2·2H2O; sodium hydrogencarbonate; ethyl acetate; water; ethyl acetate;
Reactants can be synthesized in 1 step.
Krauss, Nancy Elisabeth, US2010/324070, A1, (2010) Step 3 3,4-Diamino-5-iodo-benzoic acid methyl esterTo a solution of 4-amino-3-iodo-5-nitro-benzoic a cid methyl ester in ethyl acetate (50 mL) was added SnCl2 dihydrate. The mixture was heated to 70°C . for two hours, then cooled to room temperature and partitioned between ethyl acetate and saturated aqueous sodium bicarbonate. The organic layer was separated, dried over MgSO4, filtered and concent rated under reduced pressure to provide 1.68 g (quantitative) of 3,4-diamino-5-iodo-benzoic acid methyl ester.
